Molecules (Feb 1998)

A Short and Efficient Synthesis of (R)-Phoracantholide I

  • S. Chattopadhyay,
  • A. Sharma

DOI
https://doi.org/10.3390/30200044
Journal volume & issue
Vol. 3, no. 2
pp. 44 – 47

Abstract

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A short and efficient chemoenzymatic synthesis of the title compound has been developed. The salient features of the synthesis were i) preparation of the required chiron via a porcine pancreatic lipase (PPL) catalyzed esterification of a ω-functionalized 2-alkanol and ii) use of easily accessible and inexpensive materials/ reagents.

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