The Role of the Gut Microbiome on Skeletal Muscle Mass and Physical Function: 2019 Update

Abstract

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Within the past year, several studies have reported a positive role for the gut microbiome on the maintenance of skeletal muscle mass, evidence that contrasts previous reports of a negative role for the gut microbiome on the maintenance of whole body lean mass. The purpose of this mini-review is to clarify these seemingly discordant findings, and to review recently published studies that further elucidate the gut-muscle axis.

Keywords

• muscle strength
• endurance capacity
• microbiome
• skeletal muscle
• short chain fatty acid
• gut-muscle axis