DIAGNOSIS OF CULTURE POSITIVE URINARY TRACT INFECTIONS AND THEIR ANTIMICROBIAL SENSITIVITY PROFILE IN TERTIARY CARE CENTRE

Journal of Evidence Based Medicine and Healthcare. 2016;3(102):5650-5653 DOI 10.18410/jebmh/2016/1168

 

Journal Homepage

Journal Title: Journal of Evidence Based Medicine and Healthcare

ISSN: 2349-2562 (Print); 2349-2570 (Online)

Publisher: Level Up Business Center

Society/Institution: Level Up Business Center

LCC Subject Category: Medicine: Medicine (General): General works

Country of publisher: India

Language of fulltext: English

Full-text formats available: PDF

 

AUTHORS

Prince Sreekumar Pius (Professor, Department of General Medicine, Kanyakumari Government Medical College, Kanyakumari)
uresh Kumar (Postgraduate Student, Department of General Medicine, Kanyakumari Government Medical College, Kanyakumari.)
Manivel Ganesan (Intern, Department of General Medicine, Kanyakumari Government Medical College, Kanyakumari.)

EDITORIAL INFORMATION

Double blind peer review

Editorial Board

Instructions for authors

Time From Submission to Publication: 8 weeks

 

Abstract | Full Text

BACKGROUND Urinary tract infection is very common all over the world and in India more than 10 million cases are reported per year. It is one of the common infections diagnosed in the outpatients as well as the hospitalised patients. Empirical treatment of community acquired urinary tract infections are determined by the antibiotic sensitivity in a population. This study was conducted to determine the antimicrobial sensitivity amongst the uropathogens to help establish local guidelines on treatment of urinary tract infection. MATERIALS AND METHODS In this study, we collected 1306 samples from patients in whom we suspected to have urinary tract infection based on clinical signs and symptoms (e.g. with fever (greater than 38°C) without another explanation or from a patient who had at least one urinary symptom (dysuria, urgency, frequency, or suprapubic pain or tenderness) in our hospital during January 2016-June 2016. RESULTS Urine cultures were positive for 18% of the patients. Among these cultures, Klebsiella pneumonia (41%), Escherichia coli (35%) and Pseudomonas aeruginosa (7%) were the common organisms found. Highest antimicrobial sensitivity amongst these pathogens was found with cefoperazone/sulbactam and amikacin. CONCLUSION Cefoperazone/sulbactam and amikacin were the highly sensitive systemic antibiotics while ciprofloxacin and norfloxacin were the sensitive oral antibiotics in our locality.