CYTOKINE GENE POLYMORPHISMS AS PREDICTORS OF CHRONIC PAIN SYNDROME IN ONCOLOGY

Abstract

The literature review on the role of cytokine gene polymorphisms in the development of chronic pain in cancer patients was presented using MedLine, PubMed, NEB elibrary.ru, WileyOnlineLibrary, WebofScience, OxfordUniversityPress and SAGEPremier databases for years 1995 to 2016. The role of inter-individual differences based on cytokine gene polymorphisms and their receptors for personalized anesthetic and accompanying treatment in oncology was shown.

Keywords

• хронический болевой синдром
• онкология
• однонуклеотидный полиморфизм (онп)
• анальгетическая терапия
• обзор
• фно-α, il-1, il-6, il-10
• фармакогенетика
• ноцицепция
• цитокиновые рецепторы