mBio (Feb 2021)

Carbon Catabolite Repression in Filamentous Fungi Is Regulated by Phosphorylation of the Transcription Factor CreA

  • Leandro José de Assis,
  • Lilian Pereira Silva,
  • Ozgur Bayram,
  • Paul Dowling,
  • Olaf Kniemeyer,
  • Thomas Krüger,
  • Axel A. Brakhage,
  • Yingying Chen,
  • Liguo Dong,
  • Kaeling Tan,
  • Koon Ho Wong,
  • Laure N. A. Ries,
  • Gustavo H. Goldman

DOI
https://doi.org/10.1128/mBio.03146-20
Journal volume & issue
Vol. 12, no. 1

Abstract

Read online

In filamentous fungi, the transcription factor CreA controls carbohydrate metabolism through the regulation of genes encoding enzymes required for the use of alternative carbon sources. In this work, phosphorylation sites were identified on Aspergillus nidulans