PLoS ONE (Jan 2021)

Patient and allograft outcomes after kidney transplant for the Indigenous patients in the United States.

  • Regan Seipp,
  • Nan Zhang,
  • Sumi Sukumaran Nair,
  • Hasan Khamash,
  • Amit Sharma,
  • Scott Leischow,
  • Raymond Heilman,
  • Mira T Keddis

DOI
https://doi.org/10.1371/journal.pone.0244492
Journal volume & issue
Vol. 16, no. 2
p. e0244492

Abstract

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BackgroundThe objective is to assess cardiovascular (CV), malignancy, infectious, graft outcomes and tacrolimus levels for the Indigenous patients compared to Whites after kidney transplant (KTx).Methods165 Indigenous and 165 White patients matched for the KTx year at Mayo Clinic Arizona from 2007-2015 were studied over a median follow-up of 3 years. Propensity score was calculated to account for baseline differences.ResultsCompared to Whites, Indigenous patients had the following characteristics: younger age, more obesity, diabetes, hypertension, and required dialysis prior to KTx (pConclusionsCompared to Whites, Indigenous patients have similar CV events, graft outcomes and infectious complications after accounting for baseline differences.