Brazilian Archives of Biology and Technology (Oct 2005)

123-I ioflupane (Datscan®) presynaptic nigrostriatal imaging in patients with movement disorders

  • Angel Soriano Castrejón,
  • Ana María García Vicente,
  • Montserrat Cortés Romera,
  • Julia Vaamonde Cano,
  • Sonia Rodado Marina,
  • Victor Manuel Poblete García,
  • Sebastián Ruiz Solís,
  • María del Prado Talavera Rubio

DOI
https://doi.org/10.1590/S1516-89132005000700017
Journal volume & issue
Vol. 48, no. spe2
pp. 115 – 126

Abstract

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123-I Ioflupane (Datscan®) presynaptic imaging has been shown to have a significant utility in the assessment of patients with movement disorders 123-I Ioflupane SPECT is able to distinguish between Parkinson’s disease (PD) and other forms of parkinsonism without degeneration of the nigrostriatal pathway, including a common movement disorder such as essential tremor, and to assess disease progression in PD and other neurodegenerative disorders involving the substantia nigra.A imagem pré-sináptica através de 123-I Ioflupane (Datscan®) tem mostrado um papel significante na avaliação de pacientes com distúrbios do movimento. 123-I Ioflupane SPECT é capaz de distinguir entre Mal de Parkinson (MP) e outras formas de parkinsonismo sem degenerações da via nigroestriatal incluindo um distúrbio comum de movimento parecido com o tremor essencial e para medir a evolução da doença no Mal de Parkinson e outros distúrbios neurodegenerativos envolvendo a substantia nigra.

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