Zhongguo shuxue zazhi (Jan 2025)

Transfusion-transmitted hepatitis E

  • LI Baixun,
  • LIU Tianxu,
  • HUANG Liqin,
  • DANG Yingnan,
  • WANG Lin

DOI
https://doi.org/10.13303/j.cjbt.issn.1004-549x.2025.01.006
Journal volume & issue
Vol. 38, no. 1
pp. 38 – 42

Abstract

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Hepatitis E is an acute and self-limiting viral hepatitis caused by the hepatitis E virus (HEV). It has a higher mortality rate among immunosuppressed patients and pregnant women infected with HEV. Although HEV infections in humans are mostly caused by contaminated water or food worldwide, the incidence of transfusion-transmitted hepatitis E is continuously rising. Additionally, the prevalence of serum anti-HEV IgG in the blood donors in China is at a relatively high level, making it worth considering screening blood donors for HEV. This article briefly reviews the globally reported cases of transfusion-transmitted hepatitis E and the HEV screening strategies for blood donations.

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