Communications Biology (Jun 2022)
The Vibrio vulnificus stressosome is an oxygen-sensor involved in regulating iron metabolism
- Veronika Heinz,
- Wenke Jäckel,
- Susann Kaltwasser,
- Laura Cutugno,
- Patricia Bedrunka,
- Anica Graf,
- Alexander Reder,
- Stephan Michalik,
- Vishnu M. Dhople,
- M. Gregor Madej,
- Maria Conway,
- Marcus Lechner,
- Katharina Riedel,
- Gert Bange,
- Aoife Boyd,
- Uwe Völker,
- Richard J. Lewis,
- Jon Marles-Wright,
- Christine Ziegler,
- Jan Pané-Farré
Affiliations
- Veronika Heinz
- Department of Biophysics II/Structural Biology, University of Regensburg
- Wenke Jäckel
- Department of Microbial Physiology and Molecular Biology, University of Greifswald
- Susann Kaltwasser
- Max Planck Institute of Biophysics
- Laura Cutugno
- Discipline of Microbiology & Centre for One Health, School of Natural Sciences, Molecular Pathogenesis Research Group, National University of Ireland Galway
- Patricia Bedrunka
- Center for Synthetic Microbiology (SYNMIKRO) & Department of Chemistry, Philipps-University Marburg
- Anica Graf
- Department of Microbial Physiology and Molecular Biology, University of Greifswald
- Alexander Reder
- Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald
- Stephan Michalik
- Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald
- Vishnu M. Dhople
- Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald
- M. Gregor Madej
- Department of Biophysics II/Structural Biology, University of Regensburg
- Maria Conway
- Center for Synthetic Microbiology (SYNMIKRO) & Department of Chemistry, Philipps-University Marburg
- Marcus Lechner
- Center for Synthetic Microbiology (SYNMIKRO) & Department of Chemistry, Philipps-University Marburg
- Katharina Riedel
- Department of Microbial Physiology and Molecular Biology, University of Greifswald
- Gert Bange
- Center for Synthetic Microbiology (SYNMIKRO) & Department of Chemistry, Philipps-University Marburg
- Aoife Boyd
- Discipline of Microbiology & Centre for One Health, School of Natural Sciences, Molecular Pathogenesis Research Group, National University of Ireland Galway
- Uwe Völker
- Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald
- Richard J. Lewis
- Biosciences Institute, Newcastle University
- Jon Marles-Wright
- Biosciences Institute, Newcastle University
- Christine Ziegler
- Department of Biophysics II/Structural Biology, University of Regensburg
- Jan Pané-Farré
- Center for Synthetic Microbiology (SYNMIKRO) & Department of Chemistry, Philipps-University Marburg
- DOI
- https://doi.org/10.1038/s42003-022-03548-w
- Journal volume & issue
-
Vol. 5,
no. 1
pp. 1 – 14
Abstract
A cryo-electron microscopy reconstruction of a stressosome complex from a Gram-negative bacterium, Vibrio vulnificus, reveals variations in subunit composition and symmetry, which could serve to adjust the activation threshold in the response to low levels of oxygen and starvation.
