Molecules (Jun 2018)

Synthesis of the Sex Pheromone of the Tea Tussock Moth Based on a Resource Chemistry Strategy

  • Hong-Li Zhang,
  • Zhi-Feng Sun,
  • Lu-Nan Zhou,
  • Lu Liu,
  • Tao Zhang,
  • Zhen-Ting Du

DOI
https://doi.org/10.3390/molecules23061347
Journal volume & issue
Vol. 23, no. 6
p. 1347

Abstract

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Synthesis of the sex pheromone of the tea tussock moth in 33% overall yield over 10 steps was achieved. Moreover, the chiral pool concept was applied in the asymmetric synthesis. The synthesis used a chemical available on a large-scale from recycling of wastewater from the steroid industry. The carbon skeleton was constructed using the C4+C5+C8 strategy. Based on this strategy, the original chiral center was totally retained.

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