Química Nova (Oct 2001)

O renascimento de um fármaco: talidomida The rebirth of a drug: thalidomide

  • Lídia Moreira Lima,
  • Carlos Alberto Manssour Fraga,
  • Eliezer J. Barreiro

DOI
https://doi.org/10.1590/s0100-40422001000500016
Journal volume & issue
Vol. 24, no. 5
pp. 683 – 688

Abstract

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Thalidomide, first synthesized in 1953, was widely prescribed for morning sickness of pregnant women from 1957 to 1961, when it was found to be seriously teratogenic, having caused serious birth defect. Nowadays, a quarter of a century later, it appears that it may be a miracle drug for such diseases as leprosy, AIDS, cancer and tuberculosis.

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