Neutralizing activity of Sputnik V vaccine sera against SARS-CoV-2 variants

Satoshi Ikegame; Mohammed N. A. Siddiquey; Chuan-Tien Hung; Griffin Haas; Luca Brambilla; Kasopefoluwa Y. Oguntuyo; Shreyas Kowdle; Hsin-Ping Chiu; Christian S. Stevens; Ariel Esteban Vilardo; Alexis Edelstein; Claudia Perandones; Jeremy P. Kamil; Benhur Lee

doi:10.1038/s41467-021-24909-9

Nature Communications (Jul 2021)

Neutralizing activity of Sputnik V vaccine sera against SARS-CoV-2 variants

Satoshi Ikegame,
Mohammed N. A. Siddiquey,
Chuan-Tien Hung,
Griffin Haas,
Luca Brambilla,
Kasopefoluwa Y. Oguntuyo,
Shreyas Kowdle,
Hsin-Ping Chiu,
Christian S. Stevens,
Ariel Esteban Vilardo,
Alexis Edelstein,
Claudia Perandones,
Jeremy P. Kamil,
Benhur Lee

Affiliations

Satoshi Ikegame: Department of Microbiology at the Icahn School of Medicine at Mount Sinai
Mohammed N. A. Siddiquey: Department of Microbiology and Immunology, Louisiana State University Health Shreveport
Chuan-Tien Hung: Department of Microbiology at the Icahn School of Medicine at Mount Sinai
Griffin Haas: Department of Microbiology at the Icahn School of Medicine at Mount Sinai
Luca Brambilla: Department of Microbiology at the Icahn School of Medicine at Mount Sinai
Kasopefoluwa Y. Oguntuyo: Department of Microbiology at the Icahn School of Medicine at Mount Sinai
Shreyas Kowdle: Department of Microbiology at the Icahn School of Medicine at Mount Sinai
Hsin-Ping Chiu: Department of Microbiology at the Icahn School of Medicine at Mount Sinai
Christian S. Stevens: Department of Microbiology at the Icahn School of Medicine at Mount Sinai
Ariel Esteban Vilardo: National Administration of Laboratories and Health Institutes of Argentina (ANLIS) Dr. Carlos G. Malbrán
Alexis Edelstein: National Administration of Laboratories and Health Institutes of Argentina (ANLIS) Dr. Carlos G. Malbrán
Claudia Perandones: National Administration of Laboratories and Health Institutes of Argentina (ANLIS) Dr. Carlos G. Malbrán
Jeremy P. Kamil: Department of Microbiology and Immunology, Louisiana State University Health Shreveport
Benhur Lee: Department of Microbiology at the Icahn School of Medicine at Mount Sinai

DOI: https://doi.org/10.1038/s41467-021-24909-9
Journal volume & issue: Vol. 12, no. 1
pp. 1 – 11

Abstract

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Here, the authors characterize the neutralization capacity of post-Sputnik V vaccination sera against SARS-CoV-2 variants of concern B.1.1.7 (alpha) and B.1.351 (beta), showing the latter to exhibit resistance to neutralization in vitro.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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