Nature Communications (Oct 2019)

Transcriptomics and proteomics reveal two waves of translational repression during the maturation of malaria parasite sporozoites

  • Scott E. Lindner,
  • Kristian E. Swearingen,
  • Melanie J. Shears,
  • Michael P. Walker,
  • Erin N. Vrana,
  • Kevin J. Hart,
  • Allen M. Minns,
  • Photini Sinnis,
  • Robert L. Moritz,
  • Stefan H. I. Kappe

DOI
https://doi.org/10.1038/s41467-019-12936-6
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 13

Abstract

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Here, the authors report transcriptomes and proteomes of oocyst sporozoite and salivary gland sporozoite stages in rodent-infectious Plasmodium yoelii parasites and human infectious Plasmodium falciparum parasites and define two waves of translational repression during sporozoite maturation.