Orbital apex syndrome due to invasive aspergillosis in an immunocompetent patient
Grace D. Cullen,
Tara M. Davidson,
Zachary A. Yetmar,
Bobbi S. Pritt,
Daniel C. DeSimone
Affiliations
Grace D. Cullen
Department of Internal Medicine, Mayo Clinic, Rochester, MN, United States
Tara M. Davidson
Department of Internal Medicine, Mayo Clinic, Rochester, MN, United States
Zachary A. Yetmar
Division of Infectious Diseases, Mayo Clinic Rochester, MN, United States
Bobbi S. Pritt
Division of Infectious Diseases, Mayo Clinic Rochester, MN, United States; Division of Clinical Microbiology, Mayo Clinic, Rochester, MN, United States
Daniel C. DeSimone
Division of Infectious Diseases, Mayo Clinic Rochester, MN, United States; Department of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, United States; Corresponding author at: 200 1st Street SW, Rochester, MN, 55905, United States.
Infection is a rare cause of orbital apex syndrome (OAS) and most commonly occurs in immunocompromised hosts. We report a case of OAS in an elderly immunocompetent female due to invasive aspergillosis and Staphylococcus aureus co-infection. The patient required both surgical debridement and prolonged courses of antibiotic and antifungal therapy. Invasive fungal disease must be considered in cases of OAS, even in patients without classic risk factors.