Dissection of genetic variation and evidence for pleiotropy in male pattern baldness

Chloe X. Yap; Julia Sidorenko; Yang Wu; Kathryn E. Kemper; Jian Yang; Naomi R. Wray; Matthew R. Robinson; Peter M. Visscher

doi:10.1038/s41467-018-07862-y

Nature Communications (Dec 2018)

Dissection of genetic variation and evidence for pleiotropy in male pattern baldness

Chloe X. Yap,
Julia Sidorenko,
Yang Wu,
Kathryn E. Kemper,
Jian Yang,
Naomi R. Wray,
Matthew R. Robinson,
Peter M. Visscher

Affiliations

Chloe X. Yap: Institute for Molecular Bioscience, University of Queensland
Julia Sidorenko: Institute for Molecular Bioscience, University of Queensland
Yang Wu: Institute for Molecular Bioscience, University of Queensland
Kathryn E. Kemper: Institute for Molecular Bioscience, University of Queensland
Jian Yang: Institute for Molecular Bioscience, University of Queensland
Naomi R. Wray: Institute for Molecular Bioscience, University of Queensland
Matthew R. Robinson: Institute for Molecular Bioscience, University of Queensland
Peter M. Visscher: Institute for Molecular Bioscience, University of Queensland

DOI: https://doi.org/10.1038/s41467-018-07862-y
Journal volume & issue: Vol. 9, no. 1
pp. 1 – 12

Abstract

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Male pattern baldness (MPB) is a polygenic trait that affects the majority of European men. Here, Yap et al. estimate heritability, partitioned by autosomes and the X-chromosome, of MPB in the UK Biobank cohort, perform GWAS for MPB and find genetic correlation with other sex-specific traits.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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