Frontiers in Medicine (Apr 2024)

A false positive hair ethylglucuronide dosage in an alcohol abstinent patient after liver transplantation: a case report

  • Thierry Favrod-Coune,
  • Déborah Lidsky,
  • Julien Vionnet,
  • Giulia Magini,
  • Julien Déglon,
  • Barbara Broers

DOI
https://doi.org/10.3389/fmed.2024.1363012
Journal volume & issue
Vol. 11

Abstract

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The use of direct alcohol biomarkers (ethylglucuronide and phosphatidylethanol) has recently been implemented in a clinical setting. Due to their low alcohol detection threshold, high sensitivity, and specificity, these tools are very useful in the pre- and post-liver transplantation setting, where the history and physical signs are not always reliable. However, the interpretation of the results can sometimes be misleading and must be integrated into a global clinical evaluation and, more importantly, in the clinical context of each patient. We present here a case report illustrating a false-positive hair ethylglucuronide caused by the application of a capillary gel in an abstinent patient after liver transplantation. This reminds us that even the most accurate laboratory tests must be interpreted with caution.

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