Communications Biology (Jun 2021)
Exploring the evidence for epigenetic regulation of environmental influences on child health across generations
- Carrie V. Breton,
- Remy Landon,
- Linda G. Kahn,
- Michelle Bosquet Enlow,
- Alicia K. Peterson,
- Theresa Bastain,
- Joseph Braun,
- Sarah S. Comstock,
- Cristiane S. Duarte,
- Alison Hipwell,
- Hong Ji,
- Janine M. LaSalle,
- Rachel L. Miller,
- Rashelle Musci,
- Jonathan Posner,
- Rebecca Schmidt,
- Shakira F. Suglia,
- Irene Tung,
- Daniel Weisenberger,
- Yeyi Zhu,
- Rebecca Fry
Affiliations
- Carrie V. Breton
- Department of Preventive Medicine, Keck School of Medicine, University of Southern California
- Remy Landon
- Department of Preventive Medicine, Keck School of Medicine, University of Southern California
- Linda G. Kahn
- Department of Pediatrics, NYU Grossman School of Medicine
- Michelle Bosquet Enlow
- Department of Psychiatry, Boston Children’s Hospital and Harvard Medical School
- Alicia K. Peterson
- Department of Preventive Medicine, Keck School of Medicine, University of Southern California
- Theresa Bastain
- Department of Preventive Medicine, Keck School of Medicine, University of Southern California
- Joseph Braun
- Department of Epidemiology, Brown University School of Public Health
- Sarah S. Comstock
- Department of Food Science and Human Nutrition, Michigan State University
- Cristiane S. Duarte
- Department of Psychiatry, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center and New York State Psychiatric Institute
- Alison Hipwell
- Department of Psychiatry, University of Pittsburgh
- Hong Ji
- Department of Anatomy, Physiology and Cell Biology, School of Veterinary Medicine, California National Primate Research Center, University of California, Davis
- Janine M. LaSalle
- Department of Medical Microbiology and Immunology, MIND Institute, Genome Center, University of California, Davis
- Rachel L. Miller
- Icahn School of Medicine at Mount Sinai
- Rashelle Musci
- Department of Mental Health, Johns Hopkins Bloomberg School of Public Health
- Jonathan Posner
- Department of Psychiatry, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center and New York State Psychiatric Institute
- Rebecca Schmidt
- Department of Public Health Sciences, UC Davis School of Medicine
- Shakira F. Suglia
- Department of Epidemiology, Emory University
- Irene Tung
- Department of Psychiatry, University of Pittsburgh
- Daniel Weisenberger
- Department of Biochemistry and Molecular Medicine, University of Southern California
- Yeyi Zhu
- Division of Research, Kaiser Permanente Northern California and Department of Epidemiology and Biostatistics, University of California, San Francisco
- Rebecca Fry
- Department of Environmental Sciences and Engineering, Gillings School of Global Public Health, UNC Chapel Hill
- DOI
- https://doi.org/10.1038/s42003-021-02316-6
- Journal volume & issue
-
Vol. 4,
no. 1
pp. 1 – 15
Abstract
Carrie Breton and colleagues review the literature supporting evidence for transgenerational health effects of environmental exposures by epigenetic mechanisms. This Review summarizes current knowledge based on animal and human cohort studies, and discusses the ethical, legal, and social implications of epigenetic research in humans
