Carbohydrate Polymer Technologies and Applications (Jun 2024)

Chitosan based nanocarriers as a promising tool in treatment and management of inflammatory diseases

  • Shuchi Goyal,
  • Divya Thirumal,
  • Jaya Rana,
  • Ashok Kumar Gupta,
  • Ashok Kumar,
  • M. Arockia Babu,
  • Pradeep Kumar,
  • Rakesh K. Sindhu

Journal volume & issue
Vol. 7
p. 100442

Abstract

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Therapeutic tools in the biomedical field are increasingly utilizing nanoparticles (NPs) with a small size and large surface area. Chitosan (CS), a biotic polymeric carbohydrate found in shellfish, is a promising carrier for these diagnostic systems due to its biocompatibility, low toxic effects, and diverse shapes. CS-NPs are therapeutic transporters with properties such as bionomical, pH, and heat sensitivity, increased homogeneity, and potential to pass through the brain. These nanomaterials can detect and cure pathological conditions using curative instruments. CS-NPs slow down the movement and growth of anti-inflammatory colonies while encouraging the growth of cells causing inflammation. They could provide active substances for treating various medical conditions, such as auto-immune deformities, hyperglycemia, hypersensitivity, and cancer. Scientific resources are dedicated to improving the efficacy of CS-NP active agent compositions. Recent discoveries highlight the medicinal implications of CS-NPs preparations for drug delivery in managing severe inflammatory aberrations.

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