Correlations between the value of serum cholinesterase and Child-Pugh and Meld-Na scores in cirrhotic patients

Abstract

To determine the degree of the liver failure in cirrhotic patients we use serum liver function tests In contrast with tests, serum cholinesterase values are low in liver failure. Purpose of the study is to establish if serum cholinesterase corelates with the level of liver disfunction. According to the Child-Pugh Score, 70 patients with chronic liver disease were selected and grouped into 3 categories. Serum cholinesterase, serum albumin and International Normalized Ratio were analyzed and correlations between them were calculated. We observed that the cholinesterase levels tend to decrease according to the Child-Pugh score, lowest in the C group and highest in the A group. The cholinesterase correlated with the albumin serum levels, value of MELD-Na score and Child-Pugh score and did not corelate to INR. In conclusion, serum cholinesterase can be used as an indicator of the liver disfunction grade.

Keywords

• serum cholinesterase
• liver cirrhosis
• child-pugh score
• albumin
• meld-na score