<i>Shigella</i>
-Specific Immune Profiles Induced after Parenteral Immunization or Oral Challenge with Either Shigella flexneri 2a or Shigella sonnei

mSphere (Aug 2021)

Affiliations

Kristen A. Clarkson: ORCiD; Department of Diarrheal Disease Research, Bacterial Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA
Chad K. Porter: Naval Medical Research Center, Silver Spring, Maryland, USA
Kawsar R. Talaat: Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
Robert W. Frenck: ORCiD; Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, USA
Cristina Alaimo: LimmaTech Biologics AG, Schlieren, Switzerland
Patricia Martin: LimmaTech Biologics AG, Schlieren, Switzerland
A. Louis Bourgeois: Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
Robert W. Kaminski: ORCiD; Department of Diarrheal Disease Research, Bacterial Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA

Abstract

Although immune correlates of protection have yet to be defined for shigellosis, prior studies have demonstrated that Shigella