Enterovirus 71 Infection with Central Nervous System Involvement, South Korea

Abstract

We assessed neurologic sequelae associated with an enterovirus 71 (EV71) outbreak in South Korea during 2009. Four of 94 patients had high signal intensities at brainstem or cerebellum on magnetic resonance imaging. Two patients died of cardiopulmonary collapse; 2 had severe neurologic sequelae. Severity and case-fatality rates may differ by EV71 genotype or subgenotype.

Keywords

• Enterovirus
• central nervous system
• outbreak
• viruses
• hand-foot-and-mouth disease
• South Korea