Reactive infectious mucocutaneous eruption secondary to SARS‐CoV‐2 and influenza A coinfection with varicella zoster virus reactivation

Abstract

Abstract Reactive infectious mucocutaneous eruption (RIME) is a newly proposed clinical entity characterised by post‐infectious mucositis involving two or more mucous membranes. The term expands the previously described Mycoplasma pneumoniae‐induced rash and mucositis to include additional infectious agents. We report a case of RIME secondary to SARS‐CoV2 and Influenza A coinfection with subsequent reactivation of varicella zoster virus on the lips. RIME can have significant clinical overlap with Stevens‐Johnson Syndrome and differentiation is key in limiting unnecessary future medication restrictions on patients. This report serves to increase awareness of RIME, including to coinfections and possible reactivation of Human Herpes Viruses.

Keywords

• COVID‐19
• RIME
• SARS‐CoV2
• SJS
• TEN
• VZV