Multiplexed CRISPR technologies for gene editing and transcriptional regulation

Nicholas S. McCarty; Alicia E. Graham; Lucie Studená; Rodrigo Ledesma-Amaro

doi:10.1038/s41467-020-15053-x

Nature Communications (Mar 2020)

Multiplexed CRISPR technologies for gene editing and transcriptional regulation

Nicholas S. McCarty,
Alicia E. Graham,
Lucie Studená,
Rodrigo Ledesma-Amaro

Affiliations

Nicholas S. McCarty: Division of Biology and Biological Engineering, California Institute of Technology
Alicia E. Graham: Department of Bioengineering and Imperial College Centre for Synthetic Biology, Imperial College London
Lucie Studená: Department of Bioengineering and Imperial College Centre for Synthetic Biology, Imperial College London
Rodrigo Ledesma-Amaro: Department of Bioengineering and Imperial College Centre for Synthetic Biology, Imperial College London

DOI: https://doi.org/10.1038/s41467-020-15053-x
Journal volume & issue: Vol. 11, no. 1
pp. 1 – 13

Abstract

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Multiplexed CRISPR technologies have recently emerged as powerful approaches for genetic editing and transcriptional regulation. Here the authors review this emerging technology and discuss challenges and considerations for future studies.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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