Nature Communications (Oct 2019)

A chemically fueled non-enzymatic bistable network

  • Indrajit Maity,
  • Nathaniel Wagner,
  • Rakesh Mukherjee,
  • Dharm Dev,
  • Enrique Peacock-Lopez,
  • Rivka Cohen-Luria,
  • Gonen Ashkenasy

DOI
https://doi.org/10.1038/s41467-019-12645-0
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 9

Abstract

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Although bistability is common in biology, it is very difficult to design de novo into synthetic systems. Here, the authors present an experimental and theoretical analysis of a chemical network that displays bistable behavior under certain far-from-equilibrium conditions, and map the parameter space in which bistability operates.