Baqai Journal of Health Sciences (Jun 2016)

STUDY OF THE TOXIC EFFECTS OF CYPERMETHRIN IN EXPERIMENTAL ANIMALS

  • Syed Mehmood Hasan,
  • Moazam Ali Khan,
  • Syed Aley Hasan Zaidi

Journal volume & issue
Vol. 19, no. 1
pp. 19 – 26

Abstract

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This study focuses on the toxic effects of a commercially available pesticide, cypermethrin (CM), on animals. This pesticide was administered in the form of aerosol spray through a nebulizer. The study was performed in four different groups and a constant dose of the pesticide was administered once, twice, thrice and four times a day to the respective group for a period of 30 days. The animals were then dissected to study the pesticide effects on different organs. The organs were preserved in 10% formalin. The tissues were processed by basic histopathological method and the slides were prepared for observation. The results were recorded on a performa and were quantified by a unique scoring system. It is concluded that the injurious effects to the mentioned organs were dose and frequency dependent.

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