Establishment of a human induced pluripotent stem cell line (CSUASOi008-A) from a type 2 diabetic patient with retinopathy

Feng Tan; Chengcheng Ding; Xihao Sun; Yini Wang; Yu Peng; Yuqin Liang; Zhongping Chen; Shibo Tang; Jiansu Chen

doi:10.1016/j.scr.2021.102637

Stem Cell Research (Mar 2022)

Establishment of a human induced pluripotent stem cell line (CSUASOi008-A) from a type 2 diabetic patient with retinopathy

Feng Tan,
Chengcheng Ding,
Xihao Sun,
Yini Wang,
Yu Peng,
Yuqin Liang,
Zhongping Chen,
Shibo Tang,
Jiansu Chen

Affiliations

Feng Tan: Aier School of Ophthalmology, Central South University, P.R.C., 18th Floor, the New Century Building, #198 Furong Middle Road, Changsha, Hunan 410015, China; Aier Eye Institute, 18th Floor, The New Century Building, #198 Furong Middle Road, Changsha, Hunan 410015, China
Chengcheng Ding: Aier Eye Institute, 18th Floor, The New Century Building, #198 Furong Middle Road, Changsha, Hunan 410015, China
Xihao Sun: Aier School of Ophthalmology, Central South University, P.R.C., 18th Floor, the New Century Building, #198 Furong Middle Road, Changsha, Hunan 410015, China; Aier Eye Institute, 18th Floor, The New Century Building, #198 Furong Middle Road, Changsha, Hunan 410015, China
Yini Wang: Aier Eye Institute, 18th Floor, The New Century Building, #198 Furong Middle Road, Changsha, Hunan 410015, China
Yu Peng: Aier School of Ophthalmology, Central South University, P.R.C., 18th Floor, the New Century Building, #198 Furong Middle Road, Changsha, Hunan 410015, China
Yuqin Liang: Aier School of Ophthalmology, Central South University, P.R.C., 18th Floor, the New Century Building, #198 Furong Middle Road, Changsha, Hunan 410015, China; Aier Eye Institute, 18th Floor, The New Century Building, #198 Furong Middle Road, Changsha, Hunan 410015, China
Zhongping Chen: Aier School of Ophthalmology, Central South University, P.R.C., 18th Floor, the New Century Building, #198 Furong Middle Road, Changsha, Hunan 410015, China; Changsha Aier Eye Hospital, #388 Furong Middle Road, Changsha, Hunan 410015, China
Shibo Tang: Aier School of Ophthalmology, Central South University, P.R.C., 18th Floor, the New Century Building, #198 Furong Middle Road, Changsha, Hunan 410015, China; Aier Eye Institute, 18th Floor, The New Century Building, #198 Furong Middle Road, Changsha, Hunan 410015, China; CAS Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China; Corresponding authors at: Aier School of Ophthalmology, Central South University, P.R.C., 18th Floor, The New Century Building, #198 Furong Middle Road, Changsha, Hunan 410015, China.
Jiansu Chen: Aier School of Ophthalmology, Central South University, P.R.C., 18th Floor, the New Century Building, #198 Furong Middle Road, Changsha, Hunan 410015, China; Aier Eye Institute, 18th Floor, The New Century Building, #198 Furong Middle Road, Changsha, Hunan 410015, China; Key Laboratory for Regenerative Medicine, Ministry of Education, Jinan University, Guangzhou 510632, China; Institute of Ophthalmology, Medical College, Jinan University, Guangzhou 510632, China; Corresponding authors at: Aier School of Ophthalmology, Central South University, P.R.C., 18th Floor, The New Century Building, #198 Furong Middle Road, Changsha, Hunan 410015, China.

DOI: https://doi.org/10.1016/j.scr.2021.102637
Journal volume & issue: Vol. 59
p. 102637

Abstract

Read online

Diabetic retinopathy (DR) is one of the most common and severe microvascular complications of diabetes, and the leading cause of preventable blindness in working-aged people. Here, we generated an induced pluripotent stem (iPS) cell line using blood-derived cells from a patient with DR. Peripheral blood mononuclear cells (PBMCs) were reprogrammed with Sendai virus.

Published in Stem Cell Research

ISSN: 1873-5061 (Print); 1876-7753 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Science: Biology (General)
Website: https://www.sciencedirect.com/journal/stem-cell-research

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