Localized gastrointestinal amyloidosis presenting with protein-losing enteropathy and massive hemorrhage

Abstract

Amyloidosis of the gastrointestinal tract is usually a systemic disease. Localized gastrointestinal amyloidosis without evidence of extraintestinal involvement or an associated plasma cell dyscrasia is uncommon and does not usually cause death. We report a case of a patient with localized gastrointestinal amyloidosis who presented with protein-losing enteropathy and a fatal upper gastrointestinal bleed.

Keywords

• Amyloidosis
• Gastrointestinal bleeding
• Protein-losing enteropathy