MELATONIN AND EPILEPSY: ANALYSIS OF INFLUENCE OF PLANETARY GEOMAGNETIC FACTORS

Abstract

Objective. Influence of a solar eclipse known as "Russian", phases of the moon (full moons-new moons) on the maintenance of urinary 6 Sulfatoximelatonine (SOM) in patients with focal epilepsy and healthy is studied.Materials and Methods. 20 patients with focal epilepsy are examined: 10 during the periods of full moons and new moons – the 1st group; 10 patients with focal epilepsy (the 2nd group) and 12 healthy (the 3rd group) in the period of a solar eclipse. Concentration of the main metabolite of melatonin – a 6-Sulfatoksimelatonin (6-COM) was studied in evening and night time by an immunofermental method by means of Buhlmann 6-Sulfatoxymelatonin ELISA test system (Switzerland).Results. The night urinary excretion 6-СОМ was higher during the new moon compared to full moon 10006.5+1272 and 6421.8 +2421.7 ng, respectively. Received reliable effect of solar Eclipse on excretion night 6 SOM. During the Eclipse, compared to the next day, evening 6 SOM excretion was lower in healthy – 1.46, patients with epilepsy – in 2.47 times. Changes in morning excretion of 6 SOM were the opposite in nature: increased in the period of the Eclipse compared to the next day in healthy (28%) and epilepsy patients (27%). Conclusion. Obtained data open perspective correction of disorders melatonin status to eliminate the negative influence of the planetary geomagnetic factors.

Keywords

• focal epilepsy
• urinary 6 com
• full moon
• new moon
• solar eclipse
• melatonin status
• planetary geomagnetic factors