Development of the immune response in pneumonia due to Staphylococcus aureus (part 2)

Abstract

The article analyzes the role of pattern-recognition receptors involved in recognition of pathogen-associated molecular patterns of Staphylococcus aureus. There are shown the basic operation of macrophage and monocyte NLRP3, NLRC5, NLRP7, AIM2 inflammasomes that form the active forms of pro-inflammatory cytokines IL-1-beta and IL-18 du-ring the development of pneumonia caused by Staphylococcus aureus.

Keywords

• pneumonia
• Staphylococcus aureus
• immune response, pattern-recognition receptors
• inflammasome