Limitations of Ribotyping as Genotyping Method for Corynebacterium ulcerans

Abstract

We conducted molecular typing of a Corynebacterium ulcerans isolate from a woman who died in Japan in 2016. Genomic DNA modification might have affected the isolate’s ribotyping profile. Multilocus sequence typing results (sequence type 337) were more accurate. Whole-genome sequencing had greater ability to discriminate lineages at high resolution.

Keywords

• Corynebacterium ulcerans
• molecular typing
• genome sequence
• multilocus sequence typing
• phylogeny
• bacteria