PLoS Biology (Oct 2023)

Metabolic sinkholes: Histones as methyl repositories.

  • Ansar Karimian,
  • Maria Vogelauer,
  • Siavash K Kurdistani

DOI
https://doi.org/10.1371/journal.pbio.3002371
Journal volume & issue
Vol. 21, no. 10
p. e3002371

Abstract

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Perez and Sarkies uncover histones as methyl group repositories in normal and cancer human cells, shedding light on an intriguing function of histone methylation in optimizing the cellular methylation potential independently of gene regulation.