Arquivos de Neuro-Psiquiatria (Jul 2012)

Clinical correlates of the restless legs syndrome

  • Luis Fabiano Marin,
  • Andre Carvalho Felicio,
  • William Adolfo Santos,
  • Lucila Bizari Prado,
  • Gilmar Fernandes Prado

DOI
https://doi.org/10.1590/S0004-282X2012000700011
Journal volume & issue
Vol. 70, no. 7
pp. 529 – 531

Abstract

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OBJECTIVE: To determine the clinical correlates of the restless legs syndrome (RLS) in a Brazilian sleep disorders center. METHODS: We retrospectively studied 118 patients with RLS from January, 2004, to December, 2010. The analyzed variables were: age at disease onset, gender, race, years of school instruction, primary and secondary RLS, and treatment options. RESULTS: Among the studied patients, 83.9% were women with a female/male sex ratio of 5:1. Mean age of the patients at symptom onset ± standard deviation was 41.7±17.9 years-old. The primary RLS was found in 85% of patients. The other 15% remainders consisted of secondary forms, and they were associated with neuropathy, iron deficiency anemia, end-stage renal disease, or Parkinson's disease. Drug therapy for RLS was introduced in 67% of patients. CONCLUSIONS: Most patients presented primary RLS with an early disease onset. Further epidemiological studies are welcomed to provide better information on secondary RLS in Brazil.

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