Molecules (Apr 2013)

A Selenium-Based Ionic Liquid as a Recyclable Solvent for the Catalyst-Free Synthesis of 3-Selenylindoles

  • Eder J. Lenardão,
  • Raquel G. Jacob,
  • Samuel R. Mendes,
  • Diego Alves,
  • Gelson Perin,
  • Camilo S. Freitas,
  • Samuel Thurow,
  • Everton G. Zimmermann

DOI
https://doi.org/10.3390/molecules18044081
Journal volume & issue
Vol. 18, no. 4
pp. 4081 – 4090

Abstract

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The ionic liquid 1-butyl-3-methylimidazolium methylselenite, [bmim][SeO2(OCH3)], was successfully used as solvent in the catalyst-free preparation of 3-arylselenylindoles by the reaction of indole with ArSeCl at room temperature. The products were obtained selectively in good yields without the need of any additive and the solvent was easily reused for several cycles with good results.

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