Frontiers in Neuroscience (May 2022)
The Developing Human Connectome Project Neonatal Data Release
- A. David Edwards,
- A. David Edwards,
- Daniel Rueckert,
- Daniel Rueckert,
- Stephen M. Smith,
- Samy Abo Seada,
- Amir Alansary,
- Jennifer Almalbis,
- Joanna Allsop,
- Jesper Andersson,
- Tomoki Arichi,
- Tomoki Arichi,
- Sophie Arulkumaran,
- Matteo Bastiani,
- Matteo Bastiani,
- Dafnis Batalle,
- Dafnis Batalle,
- Luke Baxter,
- Jelena Bozek,
- Jelena Bozek,
- Eleanor Braithwaite,
- Jacqueline Brandon,
- Olivia Carney,
- Andrew Chew,
- Daan Christiaens,
- Daan Christiaens,
- Raymond Chung,
- Kathleen Colford,
- Lucilio Cordero-Grande,
- Lucilio Cordero-Grande,
- Serena J. Counsell,
- Harriet Cullen,
- Harriet Cullen,
- John Cupitt,
- Charles Curtis,
- Alice Davidson,
- Maria Deprez,
- Maria Deprez,
- Louise Dillon,
- Konstantina Dimitrakopoulou,
- Konstantina Dimitrakopoulou,
- Ralica Dimitrova,
- Ralica Dimitrova,
- Eugene Duff,
- Shona Falconer,
- Seyedeh-Rezvan Farahibozorg,
- Sean P. Fitzgibbon,
- Jianliang Gao,
- Andreia Gaspar,
- Nicholas Harper,
- Sam J. Harrison,
- Emer J. Hughes,
- Jana Hutter,
- Jana Hutter,
- Mark Jenkinson,
- Saad Jbabdi,
- Emily Jones,
- Vyacheslav Karolis,
- Vyacheslav Karolis,
- Vanessa Kyriakopoulou,
- Gregor Lenz,
- Antonios Makropoulos,
- Antonios Makropoulos,
- Shaihan Malik,
- Shaihan Malik,
- Luke Mason,
- Filippo Mortari,
- Chiara Nosarti,
- Chiara Nosarti,
- Rita G. Nunes,
- Rita G. Nunes,
- Camilla O’Keeffe,
- Jonathan O’Muircheartaigh,
- Jonathan O’Muircheartaigh,
- Jonathan O’Muircheartaigh,
- Hamel Patel,
- Jonathan Passerat-Palmbach,
- Maximillian Pietsch,
- Maximillian Pietsch,
- Anthony N. Price,
- Anthony N. Price,
- Emma C. Robinson,
- Emma C. Robinson,
- Mary A. Rutherford,
- Andreas Schuh,
- Stamatios Sotiropoulos,
- Stamatios Sotiropoulos,
- Johannes Steinweg,
- Rui Pedro Azeredo Gomes Teixeira,
- Rui Pedro Azeredo Gomes Teixeira,
- Tencho Tenev,
- Jacques-Donald Tournier,
- Jacques-Donald Tournier,
- Nora Tusor,
- Alena Uus,
- Alena Uus,
- Katy Vecchiato,
- Logan Z. J. Williams,
- Robert Wright,
- Julia Wurie,
- Joseph V. Hajnal,
- Joseph V. Hajnal
Affiliations
- A. David Edwards
- Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom
- A. David Edwards
- MRC Centre for Neurodevelopmental Disorders, King’s College London, London, United Kingdom
- Daniel Rueckert
- Biomedical Image Analysis Group, Department of Computing, Imperial College London, London, United Kingdom
- Daniel Rueckert
- Institute for AI and Informatics in Medicine, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany
- Stephen M. Smith
- Wellcome Centre for Integrative Neuroimaging, FMRIB, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom
- Samy Abo Seada
- Biomedical Engineering Department, School of Biomedical Engineering & Imaging Sciences, King’s College London, London, United Kingdom
- Amir Alansary
- Biomedical Image Analysis Group, Department of Computing, Imperial College London, London, United Kingdom
- Jennifer Almalbis
- Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom
- Joanna Allsop
- Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom
- Jesper Andersson
- Wellcome Centre for Integrative Neuroimaging, FMRIB, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom
- Tomoki Arichi
- Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom
- Tomoki Arichi
- MRC Centre for Neurodevelopmental Disorders, King’s College London, London, United Kingdom
- Sophie Arulkumaran
- Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom
- Matteo Bastiani
- Wellcome Centre for Integrative Neuroimaging, FMRIB, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom
- Matteo Bastiani
- Sir Peter Mansfield Imaging Centre, Mental Health and Clinical Neurosciences, School of Medicine, University of Nottingham, Nottingham, United Kingdom
- Dafnis Batalle
- Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom
- Dafnis Batalle
- Department of Forensic and Neurodevelopmental Sciences, Institute of Psychiatry, Psychology & Neuroscience, King’s College London, London, United Kingdom
- Luke Baxter
- Wellcome Centre for Integrative Neuroimaging, FMRIB, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom
- Jelena Bozek
- Wellcome Centre for Integrative Neuroimaging, FMRIB, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom
- Jelena Bozek
- Faculty of Electrical Engineering and Computing, University of Zagreb, Zagreb, Croatia
- Eleanor Braithwaite
- 0Centre for Brain and Cognitive Development, Department of Psychological Sciences, Birkbeck, University of London, London, United Kingdom
- Jacqueline Brandon
- Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom
- Olivia Carney
- Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom
- Andrew Chew
- Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom
- Daan Christiaens
- Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom
- Daan Christiaens
- 1Department of Electrical Engineering, ESAT/PSI, KU Leuven, Leuven, Belgium
- Raymond Chung
- 2BioResource Centre, NIHR Biomedical Research Centre, South London and Maudsley NHS Trust, London, United Kingdom
- Kathleen Colford
- Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom
- Lucilio Cordero-Grande
- Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom
- Lucilio Cordero-Grande
- 3Biomedical Image Technologies, ETSI Telecomunicación, Universidad Politécnica de Madrid and CIBER-BBN, Madrid, Spain
- Serena J. Counsell
- Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom
- Harriet Cullen
- Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom
- Harriet Cullen
- 4Department of Medical and Molecular Genetics, School of Basic and Medical Biosciences, King’s College London, London, United Kingdom
- John Cupitt
- Biomedical Image Analysis Group, Department of Computing, Imperial College London, London, United Kingdom
- Charles Curtis
- 2BioResource Centre, NIHR Biomedical Research Centre, South London and Maudsley NHS Trust, London, United Kingdom
- Alice Davidson
- Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom
- Maria Deprez
- Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom
- Maria Deprez
- Biomedical Engineering Department, School of Biomedical Engineering & Imaging Sciences, King’s College London, London, United Kingdom
- Louise Dillon
- Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom
- Konstantina Dimitrakopoulou
- Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom
- Konstantina Dimitrakopoulou
- 5Translational Bioinformatics Platform, NIHR Biomedical Research Centre, Guy’s and St. Thomas’ NHS Foundation Trust and King’s College London, London, United Kingdom
- Ralica Dimitrova
- Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom
- Ralica Dimitrova
- Department of Forensic and Neurodevelopmental Sciences, Institute of Psychiatry, Psychology & Neuroscience, King’s College London, London, United Kingdom
- Eugene Duff
- Wellcome Centre for Integrative Neuroimaging, FMRIB, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom
- Shona Falconer
- Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom
- Seyedeh-Rezvan Farahibozorg
- Wellcome Centre for Integrative Neuroimaging, FMRIB, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom
- Sean P. Fitzgibbon
- Wellcome Centre for Integrative Neuroimaging, FMRIB, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom
- Jianliang Gao
- Biomedical Image Analysis Group, Department of Computing, Imperial College London, London, United Kingdom
- Andreia Gaspar
- 6Institute for Systems and Robotics (ISR-Lisboa)/LaRSyS, Department of Bioengineering, Instituto Superior Técnico, Universidade de Lisboa, Lisbon, Portugal
- Nicholas Harper
- Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom
- Sam J. Harrison
- Wellcome Centre for Integrative Neuroimaging, FMRIB, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom
- Emer J. Hughes
- Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom
- Jana Hutter
- Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom
- Jana Hutter
- Biomedical Engineering Department, School of Biomedical Engineering & Imaging Sciences, King’s College London, London, United Kingdom
- Mark Jenkinson
- Wellcome Centre for Integrative Neuroimaging, FMRIB, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom
- Saad Jbabdi
- Wellcome Centre for Integrative Neuroimaging, FMRIB, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom
- Emily Jones
- 0Centre for Brain and Cognitive Development, Department of Psychological Sciences, Birkbeck, University of London, London, United Kingdom
- Vyacheslav Karolis
- Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom
- Vyacheslav Karolis
- Wellcome Centre for Integrative Neuroimaging, FMRIB, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom
- Vanessa Kyriakopoulou
- Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom
- Gregor Lenz
- Biomedical Image Analysis Group, Department of Computing, Imperial College London, London, United Kingdom
- Antonios Makropoulos
- Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom
- Antonios Makropoulos
- Biomedical Image Analysis Group, Department of Computing, Imperial College London, London, United Kingdom
- Shaihan Malik
- Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom
- Shaihan Malik
- Biomedical Engineering Department, School of Biomedical Engineering & Imaging Sciences, King’s College London, London, United Kingdom
- Luke Mason
- 0Centre for Brain and Cognitive Development, Department of Psychological Sciences, Birkbeck, University of London, London, United Kingdom
- Filippo Mortari
- Biomedical Image Analysis Group, Department of Computing, Imperial College London, London, United Kingdom
- Chiara Nosarti
- Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom
- Chiara Nosarti
- 7Department of Child and Adolescent Psychiatry, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, United Kingdom
- Rita G. Nunes
- Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom
- Rita G. Nunes
- 6Institute for Systems and Robotics (ISR-Lisboa)/LaRSyS, Department of Bioengineering, Instituto Superior Técnico, Universidade de Lisboa, Lisbon, Portugal
- Camilla O’Keeffe
- Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom
- Jonathan O’Muircheartaigh
- Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom
- Jonathan O’Muircheartaigh
- MRC Centre for Neurodevelopmental Disorders, King’s College London, London, United Kingdom
- Jonathan O’Muircheartaigh
- Department of Forensic and Neurodevelopmental Sciences, Institute of Psychiatry, Psychology & Neuroscience, King’s College London, London, United Kingdom
- Hamel Patel
- 2BioResource Centre, NIHR Biomedical Research Centre, South London and Maudsley NHS Trust, London, United Kingdom
- Jonathan Passerat-Palmbach
- Biomedical Image Analysis Group, Department of Computing, Imperial College London, London, United Kingdom
- Maximillian Pietsch
- Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom
- Maximillian Pietsch
- Department of Forensic and Neurodevelopmental Sciences, Institute of Psychiatry, Psychology & Neuroscience, King’s College London, London, United Kingdom
- Anthony N. Price
- Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom
- Anthony N. Price
- Biomedical Engineering Department, School of Biomedical Engineering & Imaging Sciences, King’s College London, London, United Kingdom
- Emma C. Robinson
- Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom
- Emma C. Robinson
- Biomedical Engineering Department, School of Biomedical Engineering & Imaging Sciences, King’s College London, London, United Kingdom
- Mary A. Rutherford
- Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom
- Andreas Schuh
- Biomedical Image Analysis Group, Department of Computing, Imperial College London, London, United Kingdom
- Stamatios Sotiropoulos
- Wellcome Centre for Integrative Neuroimaging, FMRIB, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom
- Stamatios Sotiropoulos
- Sir Peter Mansfield Imaging Centre, Mental Health and Clinical Neurosciences, School of Medicine, University of Nottingham, Nottingham, United Kingdom
- Johannes Steinweg
- Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom
- Rui Pedro Azeredo Gomes Teixeira
- Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom
- Rui Pedro Azeredo Gomes Teixeira
- Biomedical Engineering Department, School of Biomedical Engineering & Imaging Sciences, King’s College London, London, United Kingdom
- Tencho Tenev
- Biomedical Image Analysis Group, Department of Computing, Imperial College London, London, United Kingdom
- Jacques-Donald Tournier
- Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom
- Jacques-Donald Tournier
- Biomedical Engineering Department, School of Biomedical Engineering & Imaging Sciences, King’s College London, London, United Kingdom
- Nora Tusor
- Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom
- Alena Uus
- Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom
- Alena Uus
- Biomedical Engineering Department, School of Biomedical Engineering & Imaging Sciences, King’s College London, London, United Kingdom
- Katy Vecchiato
- Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom
- Logan Z. J. Williams
- Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom
- Robert Wright
- Biomedical Image Analysis Group, Department of Computing, Imperial College London, London, United Kingdom
- Julia Wurie
- Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom
- Joseph V. Hajnal
- Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom
- Joseph V. Hajnal
- Biomedical Engineering Department, School of Biomedical Engineering & Imaging Sciences, King’s College London, London, United Kingdom
- DOI
- https://doi.org/10.3389/fnins.2022.886772
- Journal volume & issue
-
Vol. 16
Abstract
The Developing Human Connectome Project has created a large open science resource which provides researchers with data for investigating typical and atypical brain development across the perinatal period. It has collected 1228 multimodal magnetic resonance imaging (MRI) brain datasets from 1173 fetal and/or neonatal participants, together with collateral demographic, clinical, family, neurocognitive and genomic data from 1173 participants, together with collateral demographic, clinical, family, neurocognitive and genomic data. All subjects were studied in utero and/or soon after birth on a single MRI scanner using specially developed scanning sequences which included novel motion-tolerant imaging methods. Imaging data are complemented by rich demographic, clinical, neurodevelopmental, and genomic information. The project is now releasing a large set of neonatal data; fetal data will be described and released separately. This release includes scans from 783 infants of whom: 583 were healthy infants born at term; as well as preterm infants; and infants at high risk of atypical neurocognitive development. Many infants were imaged more than once to provide longitudinal data, and the total number of datasets being released is 887. We now describe the dHCP image acquisition and processing protocols, summarize the available imaging and collateral data, and provide information on how the data can be accessed.
Keywords
