Nature Communications (Nov 2022)

Molecular identity of proprioceptor subtypes innervating different muscle groups in mice

  • Stephan Dietrich,
  • Carlos Company,
  • Kun Song,
  • Elijah David Lowenstein,
  • Levin Riedel,
  • Carmen Birchmeier,
  • Gaetano Gargiulo,
  • Niccolò Zampieri

DOI
https://doi.org/10.1038/s41467-022-34589-8
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 11

Abstract

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The molecular basis of proprioceptive neuron subtype identities is not fully understood. Here the authors investigate diversity of proprioceptive neurons connected to different muscles at the molecular level, and show that acquisition of muscle-type identity precedes the emergence of receptor character and contains effectors controlling muscle connectivity.