ALGORITHM FOR DIAGNOSING WILLEBRAND'S DISEASE

Abstract

Willebrand's disease is the most common hereditary coagulopathy caused by a decrease in the amount or impaired function of Willebrand factor (vWF). It occurs in 0.5-1 % of the population, the prevalence of clinically significant forms is 1-2 per 10000 people. Depending on the nature of Willebrand factor disorders, there are three main types of Willebrand's disease. Each of these categories corresponds to certain pathophysiological mechanisms, which largely correlate with clinical features and therapeutic requirements. Cooperation of the Kuzbass Clinical Hospital and ROSMED online platforms.INFO in 2021 allowed the second stage of diagnosis to be carried out by laboratory testing of specific coagulological tests for the diagnosis of the type of Willebrand's disease. The study made it possible to verify the diagnosis of Willerbrand's disease depending on the type and to make a correction in therapy.

Keywords

• болезнь виллебранда
• диагностический алгоритм