Effect of Occupational Stress on Periodontitis According to the Salivary RANKL Level Among Iraqi Employees

Abstract

Athraa Ali Mahmood,1 Hussain Owaid Muhammed Al-Obadi,1 Hashim Mueen Hussein2 1Department of Oral Surgery and Periodontics, College of Dentistry, Mustansiriyah University, Baghdad, Iraq; 2Department of Conservative Dentistry, College of Dentistry, Mustansiriyah University, Baghdad, IraqCorrespondence: Athraa Ali Mahmood, Department of Oral Surgery and Periodontics, College of Dentistry, Mustansiriyah University, Baghdad, Iraq, Email [email protected]; [email protected]: Findings show that periodontitis does not affect all populations; similarly, some individuals present risk conditions such as occupational stress, making them more susceptible to developing periodontitis through unhealthy habits like poor oral hygiene and immune suppression. Periodontitis triggers an inflammatory host immune response; “Receptor Activator Nuclear Factor KB ligand (RANKL)” is the primary regulator of osteoclast differentiation and activity. It was found that osteoclastic bone damage caused by periodontitis depends on the RANKL produced by osteoblastic and periodontal ligament cells.Objective: This study aimed to assess the effect of occupational stress on employees with periodontitis using salivary RANKL marker.Material and Methods: A case–control analysis was done at my clinic with 90 male employees aged 30– 50. The participants completed self-administered questionnaires and had periodontal exams. Employee occupational stress was estimated using a life events scale questionnaire. Calibrated dentists performed the parameters used in the periodontal assessment after collecting whole unstimulated salivary samples from each employee to measure salivary RANKL using ELISA technique.Results: The present finding revealed a statistically significant difference among groups in “probing pocket depth, plaque index, bleeding on probing, clinical attachment level, and salivary RANKL level”. They were higher in the stressed employees’ group, which is not statistically significant.Conclusion: The findings of this investigation observed that occupational stress increased clinical periodontal parameters and salivary RANKL of periodontitis in employees.Keywords: periodontitis, occupational stress, salivary RANKL, employees

Keywords

• periodontitis
• occupational stress
• salivary rankl
• employees.