Determination of Residual Triflumezopyrim Insecticide in Agricultural Products through a Modified QuEChERS Method
Sung-Min Cho,
Han-Sol Lee,
Ji-Su Park,
Su-Jung Lee,
Hye-Sun Shin,
Yun-Mi Chung,
Ha-Na Choi,
Yong-Hyun Jung,
Jae-Ho Oh,
Sang-Soon Yun
Affiliations
Sung-Min Cho
Food Safety Evaluation Department, Pesticide and Veterinary Drug Residues Division, National Institute of Food and Drug Safety Evaluation, Ministry of Food and Drug Safety, Cheongju 28159, Korea
Han-Sol Lee
Food Safety Evaluation Department, Pesticide and Veterinary Drug Residues Division, National Institute of Food and Drug Safety Evaluation, Ministry of Food and Drug Safety, Cheongju 28159, Korea
Ji-Su Park
Food Safety Evaluation Department, Pesticide and Veterinary Drug Residues Division, National Institute of Food and Drug Safety Evaluation, Ministry of Food and Drug Safety, Cheongju 28159, Korea
Su-Jung Lee
Food Safety Evaluation Department, Pesticide and Veterinary Drug Residues Division, National Institute of Food and Drug Safety Evaluation, Ministry of Food and Drug Safety, Cheongju 28159, Korea
Hye-Sun Shin
Food Safety Evaluation Department, Pesticide and Veterinary Drug Residues Division, National Institute of Food and Drug Safety Evaluation, Ministry of Food and Drug Safety, Cheongju 28159, Korea
Yun-Mi Chung
Hazardous Substances Analysis Division, Gwangju Regional Food and Drug Administration, Gwangju 61012, Korea
Ha-Na Choi
Hazardous Substances Analysis Division, Gwangju Regional Food and Drug Administration, Gwangju 61012, Korea
Yong-Hyun Jung
Food Safety Evaluation Department, Pesticide and Veterinary Drug Residues Division, National Institute of Food and Drug Safety Evaluation, Ministry of Food and Drug Safety, Cheongju 28159, Korea
Jae-Ho Oh
Food Safety Evaluation Department, Pesticide and Veterinary Drug Residues Division, National Institute of Food and Drug Safety Evaluation, Ministry of Food and Drug Safety, Cheongju 28159, Korea
Sang-Soon Yun
Food Safety Evaluation Department, Pesticide and Veterinary Drug Residues Division, National Institute of Food and Drug Safety Evaluation, Ministry of Food and Drug Safety, Cheongju 28159, Korea
A rapid and simple analytical method for triflumezopyrim, a new class of mesoionic insecticides and commercialized molecules from DuPont, was developed with a modified QuEChERS method. The pH adjustment was used to improve the extraction efficiency of acetonitrile solvent, and dispersive solid-phase extraction was employed for the clean-up process. The five selected food commodities were used to verify the present optimized method, which displayed good linearity with an excellent correlation coefficient (R2 = 0.9992–0.9998) in the 0.003–0.30 mg/kg calibration range. The method limits of detection (LOD) and quantification (LOQ) were determined to be a value of 0.003 and 0.01 mg/kg, respectively. The mean recovery for the triflumezopyrim was in the 89.7–104.3% range. The relative standard deviations were ≤9.8% for intra- (n = 5) and inter-day (n = 15) precisions at concentrations of 0.01, 0.1, and 0.5 mg/kg in the five representative samples. The matrix effect has been calculated to confirm the effect during ionization of the analyte in the UPLC-MS/MS. The matrix effects of the instrumental analysis showed that triflumezopyrim was less susceptible to matrices. The proposed analytical method in this study has effectively improved the accuracy, selectivity, and sensitivity for the determination of triflumezopyrim in agricultural commodities; therefore, it can serve as a reference method for the establishment of maximum residue limits (MRLs).