Communications Biology (Jan 2021)

Optimal combination treatment regimens of vaccine and radiotherapy augment tumor-bearing host immunity

  • Fayun Zhang,
  • Zifeng Zheng,
  • Apurba Kumar Barman,
  • Zihao Wang,
  • Luyao Wang,
  • Wenfeng Zeng,
  • Luoyang Wang,
  • Yan Qin,
  • Asmita Pandey,
  • Chunling Zhang,
  • Wei Liang

DOI
https://doi.org/10.1038/s42003-020-01598-6
Journal volume & issue
Vol. 4, no. 1
pp. 1 – 14

Abstract

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Zhang et al. use mouse tumor models to show that the optimum treatment regime for Treg-induced radiation resistance is vaccine administration followed by radiation therapy. This finding could inform the design of future combinatorial cancer therapies in the clinic.