Vitreoretinal biomarkers of retinopathy of prematurity using handheld optical coherence tomography: a review

Deepika Kubsad; Masis A. Ohan; Jolan G. Wu; Michelle T. Cabrera; Michelle T. Cabrera

doi:10.3389/fped.2023.1191174

Frontiers in Pediatrics (May 2023)

Vitreoretinal biomarkers of retinopathy of prematurity using handheld optical coherence tomography: a review

Deepika Kubsad,
Masis A. Ohan,
Jolan G. Wu,
Michelle T. Cabrera,
Michelle T. Cabrera

Affiliations

Deepika Kubsad: University of Washington School of Medicine, Seattle, WA, United States
Masis A. Ohan: University of Washington School of Medicine, Seattle, WA, United States
Jolan G. Wu: Department of Ophthalmology, University of Washington, Seattle, WA, United States
Michelle T. Cabrera: Department of Ophthalmology, University of Washington, Seattle, WA, United States
Michelle T. Cabrera: Division of Ophthalmology, Seattle Children's Hospital, Seattle, WA, United States

DOI: https://doi.org/10.3389/fped.2023.1191174
Journal volume & issue: Vol. 11

Abstract

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Retinopathy of prematurity (ROP) is caused by abnormal retinal vascularization in premature infants that has the potential for severe long-term vision impairment. Recent advancements in handheld optical coherence tomography (OCT) have enabled noninvasive, high-resolution, cross-sectional imaging of the infant eye at the bedside. The use of handheld OCT devices in the diagnosis of ROP in premature infants has furthered our understanding of disease state and progression. This review discusses the known and novel biomarkers of ROP severity in premature infants identified through handheld OCT and potential for future directions.

Published in Frontiers in Pediatrics

ISSN: 2296-2360 (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Medicine: Pediatrics
Website: http://journal.frontiersin.org/journal/pediatrics

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Abstract

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