Checkpoint blockade-induced CD8+ T cell differentiation in head and neck cancer responders

• Zhe Zhang,
• Yi Zhang,
• Fan Zhang,
• Xiaojing Ma,
• Ravindra Uppaluri,
• Robert Haddad,
• Jonathan D Schoenfeld,
• Shengqing Gu,
• Joshua Keegan,
• James A Lederer,
• Xiaoqing Wang,
• Zexian Zeng,
• Jingxin Fu,
• Liye Zhou,
• Ann Marie Egloff,
• Fei Guo,
• Katie M Campbell,
• Peter Du,
• Paul Zolkind,
• Rachel Riley,
• Yasutaka Nakahori,
• Obi Griffith,
• Robert T Manguso,
• X Shirley Liu

Affiliations

Zhe Zhang

Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China

Yi Zhang

Department of Ophthalmology, Sichuan University West China Hospital, Chengdu, Sichuan, China

Fan Zhang

Department of Surgery, Brigham and Women`s Hospital, Boston, Massachusetts, USA

Xiaojing Ma

Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai Clinical Center for Diabetes, Shanghai Key Clinical Center for Metabolic Disease, Shanghai Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai, China

Ravindra Uppaluri

Aff13 0000 0004 0378 8294grid.62560.37Brigham and Women’s Hospital and Dana-Farber Cancer Institute Boston MA USA

Robert Haddad

Aff3 grid.65499.370000000121069910Dana Farber Cancer Institute Boston MA USA

Jonathan D Schoenfeld

Aff2 grid.48336.3a0000000419368075Dana-Farber/Harvard Cancer Center Boston MA USA

Shengqing Gu

4 Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, MA, USA

Joshua Keegan

1Brigham and Women’s Hospital and Harvard Medical School, Boston, MA, USA

James A Lederer

1Brigham and Women’s Hospital and Harvard Medical School, USA

Xiaoqing Wang

1Dana-Farber Cancer Institute, Boston, MA, United States

Zexian Zeng

1Dana-Farber Cancer Institute, Boston, MA, United States

Jingxin Fu

1Dana-Farber Cancer Institute, Boston, MA, United States

Liye Zhou

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA

Ann Marie Egloff

Department of Surgery, Brigham and Women`s Hospital, Boston, Massachusetts, USA

Fei Guo

Department of Surgery, Brigham and Women`s Hospital, Boston, Massachusetts, USA

Katie M Campbell

Department of Medicine, University of California Los Angeles, Los Angeles, California, USA

Peter Du

Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA

Paul Zolkind

Department of Otolaryngology, Washington University in St Louis School of Medicine, St Louis, Missouri, USA

Rachel Riley

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA

Yasutaka Nakahori

Department of Surgery, Brigham and Women`s Hospital, Boston, Massachusetts, USA

Obi Griffith

McDonnell Genome Institute and Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA

Robert T Manguso

Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA

X Shirley Liu

Department of Data Science, Dana-Farber Cancer Institute, Boston, Massachusetts, USA