Prevalence of refractive errors in children with retinoblastoma

Abstract

Victor M Villegas,1,2 Shuo-Chieh Wu,1 Timothy G Murray,2 Kara M Cavuoto,1 Hilda Capo,1 Craig A McKeown1 1Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, FL, USA; 2Miami Ocular Oncology and Retina, Miami, FL, USA Purpose: The main purpose of this study was to investigate refractive errors in children with unilateral and bilateral retinoblastoma (RB).Methods: An institutional review board–approved consecutive retrospective cohort study was undertaken. Subjects underwent examination under general anesthesia as part of their RB follow-up, which included evaluation by a single pediatric ophthalmologist. Cycloplegic retinoscopy was performed and keratometry data assessed with a handheld Retinomax K Plus 3 keratorefractometer (Righton Ophthalmic Instruments).Results: The study included 61 eyes of 37 subjects, with 18 (49%) males and 19 females. Seventeen eyes (28%) had hyperopia with spherical equivalent ≥3 D. Refractive astigmatism ≥1.5 D was present in 32% of all eyes. Nine (38%) subjects had anisometropia ≥2 D. Fifteen (63%) subjects had anisometropia ≥1 D.Conclusion: This study reports the high proportion of amblyogenic refractive risk factors in children with RB, both in RB-affected eyes and contralateral normal eyes. Keywords: retinoblastoma, hyperopia, myopia, astigmatism, amblyopia, anisometropia  

Keywords

• retinoblastoma
• hyperopia
• myopia
• astigmatism
• amblyopia
• anisometropia