FEATURES OF NASAL MICROBIOTA IN PATIENTS WITH RESPIRATORY ATOPY AND PSEUDOATOPY DEPENDING ON THE LEVEL OF INJURY OF RESPIRATORY TRACT

Abstract

Comparative characteristic of the nasal microbiota in respiratory atopy and pseudoatropy depending on the level of the lesion respiratory tract. The study involved: true atopic rhinosinusitis (IAR, n=27), atopic bronchial asthma (BA, n=27), polypous rhinosinusitis (PRS, n=67) and deployed asthmatic triad (RAT; n=27).Control – healthy nasal microbiota donors, from 19 to 63 years, comparable in sex and age with patients. Microbiota with the mucosa grown on differential diagnostic media. Highlighting the genesis and level of damage to the respiratory tract in allergies, rhinosinusitis determined a high concentration of representatives of the genus Enterobacteriaceae in IAR relative to PRS. For the lower respiratory tract, a high concentration of Enterococcus genus in the BA group relative to RAT was established. The total amount of microbiota is higher in atopic inflammation of the respiratory tract (AR and BA) relative to the control.

Keywords

• микробиота
• атопический риносинусит
• атопическая бронхиальная астма
• астматическая триада
• полипозный риносинусит