Unilateral rubral tremors in Wilson′s disease treated with dimercaprol

Abstract

Tremors are reported as the most frequent neurological manifestation of Wilson′s disease (WD) in some series. Postural tremors, rest tremors, action tremors and wing-beating (rubral) tremors are the different types of tremors seen in WD. We report a patient of WD with unilateral rubral tremors refractory to 1-year therapy with Penicillamine and anti-tremor medications. The tremors decreased considerably after adding chelation therapy with dimercaprol. Combination of Penicillamine and dimercaprol is an effective decoppering measure in rubral tremors of WD.

Keywords

• Wilson′s disease
• BAL
• dimercaprol
• chelation
• rubral tremors