Journal of Personalized Medicine (Sep 2022)

Depressive Symptoms in Expecting Fathers: Is Paternal Perinatal Depression a Valid Concept? A Systematic Review of Evidence

  • Marianna Mazza,
  • Georgios D. Kotzalidis,
  • Carla Avallone,
  • Marta Balocchi,
  • Ilenia Sessa,
  • Ilaria De Luca,
  • Daniele Hirsch,
  • Alessio Simonetti,
  • Delfina Janiri,
  • Emanuela Loi,
  • Giuseppe Marano,
  • Gabriella Albano,
  • Vittorio Fasulo,
  • Stefania Borghi,
  • Angela Gonsalez del Castillo,
  • Anna Maria Serio,
  • Laura Monti,
  • Daniela Chieffo,
  • Gloria Angeletti,
  • Luigi Janiri,
  • Gabriele Sani

DOI
https://doi.org/10.3390/jpm12101598
Journal volume & issue
Vol. 12, no. 10
p. 1598

Abstract

Read online

Background. Since the identification of Couvade syndrome in the late 1950s, little attention has been dedicated to the issue of depression in expecting fathers. Objective. To quantify the extent of depression in expecting fathers and find out if they match their pregnant partners’ depression. Methods. We conducted a PubMed and ClinicalTrials.gov search using paternal depression and all its variants as terms. We used the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 statement to include eligible studies. Results. We identified a grand total of 1443 articles, of which 204 were eligible. The total number of fathers/expecting fathers involved was 849,913. Longitudinal studies represented more than half of the included studies; more than three-quarters of the studies used the Edinburgh Postnatal Depression Scale (EPDS). The average occurrence of paternal depression was around 5%, which confers the entity some clinical dignity. Depression tends to occur more in expecting women and new mothers than in expecting partners or new fathers, while the co-occurrence in the same couple is quite low. Limitations. The methodological heterogeneity of the included studies prevents us from meta-analyzing the obtained data. The validity of the instruments used is another issue. Conclusions. Paternal depression is distinct from maternal depression and occurs at lower rates (about half). The very existence of a paternal depression clinical entity is beyond any doubt. Future research should address methodological heterogeneity.

Keywords