Calotropis-induced corneal toxicity in Indian medicinal use: A rare case report with review of literature

Abstract

The use of Calotropis plant is widespread in the Indian system of Medicine (Ayurveda) and for religious purpose as an offering to Hindu god. Having an advantage of growing abundantly in unfavorable and harsh atmosphere, this shrub is easily found in many Indian states. We report here a case, in which a young boy developed severe corneal edema in both eyes following the application of Calotropis latex over the scalp area for the treatment of alopecia as prescribed by some Ayurveda practitioner. Patient responded well with the treatment including topical steroids with a complete resolution of corneal edema and persistent endothelial cell loss at the end of 6 weeks. This case report highlights the possibility of Calotropis-induced corneal endothelial toxicity while using it as an Ayurveda remedy and its management. Public education is must regarding this particularly in India where the use and availability of Calotropis shrub is widespread.

Keywords

• ayurveda medicine
• calotropis procera
• corneal toxicity
• endothelial toxicity
• madar