Nature Communications (Jan 2016)

The novel tumour suppressor Madm regulates stem cell competition in the Drosophila testis

  • Shree Ram Singh,
  • Ying Liu,
  • Jiangsha Zhao,
  • Xiankun Zeng,
  • Steven X. Hou

DOI
https://doi.org/10.1038/ncomms10473
Journal volume & issue
Vol. 7, no. 1
pp. 1 – 12

Abstract

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Stem cell competition mediates the balance between tissue homeostasis and tumour formation, but how this occurs is unclear. Here, Singh et al.show that the tumour suppressor Mlfl-adaptor molecule regulates the balance between germline stem cell and somatic cyst stem cell growth in the Drosophila testis niche.