IL-10 Polymorphism and Breast Cancer Risk in Georgian Women: A Case–Control Study

Ahmadi Ahmadi; Surmava Surmava; Kvaratskhelia Kvaratskhelia; Abzianidze Abzianidze; Kankava Kankava

doi:10.1055/s-0043-1770957

Global Medical Genetics (Sep 2023)

IL-10 Polymorphism and Breast Cancer Risk in Georgian Women: A Case–Control Study

Ahmadi Ahmadi,
Surmava Surmava,
Kvaratskhelia Kvaratskhelia,
Abzianidze Abzianidze,
Kankava Kankava

Affiliations

Ahmadi Ahmadi: Department of Molecular and Medical Genetics, Tbilisi State Medical University, Tbilisi, Georgia
Surmava Surmava: Department of Molecular and Medical Genetics, Tbilisi State Medical University, Tbilisi, Georgia
Kvaratskhelia Kvaratskhelia: Department of Molecular and Medical Genetics, Tbilisi State Medical University, Tbilisi, Georgia
Abzianidze Abzianidze: Department of Molecular and Medical Genetics, Tbilisi State Medical University, Tbilisi, Georgia
Kankava Kankava: Department of Molecular and Medical Genetics, Tbilisi State Medical University, Tbilisi, Georgia

DOI: https://doi.org/10.1055/s-0043-1770957
Journal volume & issue: Vol. 10, no. 03
pp. 159 – 163

Abstract

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Background Interleukin-10 (IL-10) is a cytokine with a vast variety of functions, but its role in cancer development and progression is not yet clear. It is involved in two of the hallmarks of cancer: vascularization and immune modulation. IL-10 inhibits angiogenesis and hence is antitumorigenic. But it also can suppress the immune system and be tumorigenic.

Published in Global Medical Genetics

ISSN: 2699-9404 (Online)
Publisher: Georg Thieme Verlag KG
Country of publisher: Germany
LCC subjects: Science: Biology (General): Genetics; Medicine: Internal medicine: Neoplasms. Tumors. Oncology. Including cancer and carcinogens
Website: https://www.thieme.com/books-main/genetics/product/5705-global-medical-genetics

About the journal

Abstract

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