Correlation between visceral fat area and carotid atherosclerotic plaque in patients with type 2 diabetes mellitus

Abstract

"Objective To investigate the effect of visceral fat area (VFA) on carotid atherosclerotic plaque in patients with type 2 diabetes mellitus(T2DM). Methods From August 2018 to August 2023, 683 T2DM patients included in the database of the National Metabolic Management Center (MMC) were selected from the Department of Endocrinology, the Affiliated Geriatric Hospital of Nanjing Medical University. Medical history, physical examination, serum biochemical indicators, VFA and other data were collected from the study subjects. According to the presence or absence of carotid atherosclerotic plaque, all patients were divided into T2DM patients with plaque (n=342) and T2DM patients without plaque (n=341), and statistical analysis was performed. Results There were statistically significant differences in age, body mass index (BMI), waist circumference, diastolic blood pressure (DBP), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), abdominal subcutaneous fat area (SFA) and VFA between the two groups (PConclusion Age and VFA are independent influencing factors for atherosclerotic plaque formation in patients with T2DM，and as a new obesity assessment index, VFA can better predict and assess the risk of atherosclerotic plaque formation in T2DM patients."

Keywords

• type 2 diabetes mellitus， atherosclerosis， obesity，visceral fat area， abdominal subcutaneous fat area， body mass index， waist circumference