ELECTROCARDIOGRAPHIC ASPECTS OF SECONDARY CARDIOMYOPATHY IN HEPATIC PARENCHYMAL DISEASE, AND THEIR ASSOCIATION WITH THE LEADING HEPATIC SYNDROME

Abstract

In 68 patients with clinical, anamnestic, laboratory, and ultrasound evidence of chronic hepatic parenchymal disease and secondary cardiomyopathy, a range of electrocardiographic parameters was investigated, in accordance with the leading hepatic syndrome. Among the individuals with hepatic secondary cardiomyopathy, the most informative parameters, determining the severity and prognosis of the disease, were the following: the number of supraventricular and ventricular extrasystoles; myocardial ischemia duration; segment ST depression/elevation area; QT interval dispersion; and temporal parameters of heart rate variability. These parameters were more disturbed in patients with the leading syndromes of cytolysis and cholestasis, in comparison to the participants with the leading syndromes of hepato-cellular failure.

Keywords

• chronic hepatic parenchymal disease
• hepatic secondary cardiomyopathy
• hepatic syndromes: cytolysis, cholestasis, hepato-cellular failure
• supraventricular and ventricular extrasystoles
• qualitative and quantitative parameters of transient myocardial ischemia
• qt interval dispersion
• heart rate variability